Which vitamin deficiency can lead to rickets in children?

Rickets in children is primarily associated with a deficiency of vitamin D. This vitamin plays a crucial role in calcium and phosphate metabolism, which are essential for the development and mineralization of healthy bones. When there is insufficient vitamin D, the body struggles to absorb calcium from the diet, leading to calcium and phosphate deficiencies. As a result, the bones remain soft and weak, which manifests as rickets, characterized by delayed growth, bone deformities, and an increased risk of fractures.

Vitamin A is important for many bodily functions, including vision and immune function, but it does not directly influence bone mineralization to the extent that vitamin D does. Vitamin B12 is vital for red blood cell formation and neurological function, while vitamin K is essential for proper blood clotting and bone health. However, neither of these vitamins has a direct role in preventing rickets.

Therefore, the deficiency of vitamin D is the key factor leading to the development of rickets in children.