University of Central Florida (UCF) HSC4558 Pathophysiology II Final Practice Exam

Hashimoto's thyroiditis is an autoimmune disorder that leads to the destruction of thyroid tissue, resulting in hypothyroidism. The primary treatment for this condition focuses on addressing the resultant low levels of thyroid hormone due to the damage inflicted on the thyroid gland.

Thyroid hormone replacement therapy provides the body with the necessary hormones that the damaged gland can no longer produce adequately. This treatment typically involves medications such as levothyroxine, which is a synthetic form of thyroxine (T4). By supplementing these hormones, the therapy helps to restore normal metabolic function and alleviate symptoms associated with hypothyroidism, such as fatigue, weight gain, and cold intolerance.

Other approaches like anti-thyroid drugs or radioactive iodine ablation are more pertinent to conditions where there is excess production of thyroid hormones, such as in hyperthyroidism or Graves' disease, rather than in Hashimoto's thyroiditis, where the gland is underactive. Surgery may be considered in cases of significant goiter or malignancy, but it is not the primary treatment for Hashimoto's. Thus, thyroid hormone replacement is the most appropriate and widely accepted treatment strategy for managing this condition effectively.