Which set of symptoms may indicate hypoparathyroidism?

Hypoparathyroidism is characterized by low levels of parathyroid hormone (PTH), which leads to decreased levels of calcium in the blood (hypocalcemia). This condition can manifest through neurological symptoms due to the effect of low calcium on nerve function.

Circumoral numbness and paresthesias are common neurological symptoms associated with hypoparathyroidism. These sensations occur due to the irritation of nerves or muscle function impairment caused by low calcium levels. The term "circumoral" refers specifically to numbness around the mouth, while "paresthesias" can refer to a tingling or "pins and needles" sensation which may affect other parts of the body as well.

In contrast, elevated calcium levels and anxiety, weight loss and bradycardia, or osteoporosis and dehydration do not correlate with the underlying pathophysiology of hypoparathyroidism. Elevated calcium levels are typically seen in conditions like hyperparathyroidism, whereas weight loss and bradycardia might suggest thyroid dysfunctions or other metabolic disorders rather than hypoparathyroidism itself. Osteoporosis can occur with prolonged hypoparathyroidism due to the ongoing imbalance of calcium regulation, but dehydration is not a direct symptom associated with this condition.