Which hormone is responsible for inhibiting insulin and glucagon?

Somatostatin is the hormone that inhibits the release of both insulin and glucagon from the pancreas. It plays a critical role in regulating glucose metabolism and maintaining homeostasis in the body. By inhibiting these two hormones, somatostatin helps to ensure that blood sugar levels remain stable, preventing excessive spikes or drops.

Insulin is primarily responsible for lowering blood glucose levels, while glucagon raises them by promoting glucose release from the liver. Somatostatin acts as a balancing agent, preventing an overreaction in either direction. It is secreted by the delta cells of the pancreas and functions as part of the endocrine system to finely tune metabolic processes.

The significance of somatostatin lies in its ability to moderate the hormonal responses, facilitating a coordinated endocrine activity that is crucial for effective metabolic regulation. The other options, while important hormones, do not have the specific function of directly inhibiting both insulin and glucagon secretion.