What mental changes characterize myxedema?

Myxedema, a severe form of hypothyroidism, is characterized by a range of physical and mental changes due to insufficient thyroid hormone levels. One of the hallmark mental changes associated with myxedema is an altered mental state. This can manifest as confusion, decreased cognitive function, depression, lethargy, and, in extreme cases, coma. The lack of thyroid hormones affects various brain functions, leading to these cognitive impairments.

In contrast, significant weight gain can occur due to slowed metabolism associated with hypothyroidism, but it is not primarily a direct mental change. The progressive decline in physical strength is a physical symptom rather than a mental one. Improved cognitive function is the opposite of what typically happens in myxedema, as patients often struggle with mental clarity and cognitive performance due to the impact of low thyroid hormones. Therefore, altered mental state is the most accurate reflection of the mental changes seen in myxedema.