What is the primary treatment approach for H. pylori infection in peptic ulcer disease?

The primary treatment approach for H. pylori infection in peptic ulcer disease is the use of antibiotics. H. pylori is a type of bacteria that can infect the stomach lining and is a significant contributing factor to the development of peptic ulcers. The eradication of this bacterium is essential in promoting the healing of ulcers and preventing their recurrence.

Antibiotic therapy typically involves a combination of drugs to increase effectiveness and reduce the chance of resistance. This dual or triple antibiotic regimen, often accompanied by a proton pump inhibitor, not only targets the bacteria directly but also reduces gastric acid secretion, creating a more favorable environment for healing.

Surgery is not a first-line treatment for H. pylori infections or peptic ulcer disease unless there are complications, such as bleeding or perforation, that cannot be managed medically. Dietary changes may help manage symptoms but do not directly address the underlying bacterial infection. Physical therapy is not relevant to the treatment of H. pylori or peptic ulcers. Therefore, the use of antibiotics stands out as the primary and most effective treatment strategy for H. pylori-related peptic ulcer disease.